What is Protein Data Bank (PDB)

 Protein Data Bank (PDB)

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

The Protein Data Bank (PDB) is a database of three-dimensional structures of proteins, nucleic acids, and complex biological assemblies, maintained by the Worldwide Protein Data Bank (wwPDB). It is one of the most important and widely used biological databases in the field of structural biology.

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

The PDB database contains detailed information on the 3D structures of proteins and other biomolecules, obtained through techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy (cryo-EM). Each structure in the database is accompanied by metadata, such as the source organism, experimental conditions, and relevant scientific literature.

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

The PDB database is freely accessible to researchers around the world and can be searched and downloaded through the wwPDB website. Researchers use the database for a wide range of purposes, such as:

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

Identifying and obtaining 3D structures of proteins and other biomolecules of interest for their research

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

Analyzing the structural features and interactions of proteins and other biomolecules to understand their function and mechanism of action

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

Designing new drugs and therapeutics by studying the interactions between small molecules and proteins

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

Developing and testing computational tools for protein structure prediction and analysis

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

The PDB database is updated regularly with new structures, which are submitted by researchers from around the world. The database also provides a variety of tools and resources for protein structure analysis and visualization, such as molecular visualization software and tutorials on structural biology.

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB

In addition to the PDB database, the wwPDB maintains several other databases, such as the Electron Microscopy Data Bank (EMDB), which contains cryo-EM structures, and the Protein Structure Initiative Structural Genomics Knowledgebase (PSI SGKB), which provides information on the structural genomics projects. These databases complement and interconnect with the PDB to provide a comprehensive resource for researchers in the field of structural biology.

Protein Data Bank PDB Protein Data Bank PDB Protein Data Bank PDB



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